Description

(2E)-N-(2-Cyanophenyl)-3-(Thiophen-2-yl)prop-2-enamide is a specialized organic compound featuring a conjugated enamide structure linked to cyanophenyl and thiophene moieties. This unique molecular architecture makes it a valuable advanced pharmaceutical intermediate and a versatile building block in synthetic organic chemistry. It is primarily required by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for the synthesis of novel active compounds and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, particularly those targeting neurological or oncological pathways.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic components for bioactivity.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, cyclizations, and as a scaffold for constructing complex heterocyclic systems.
• Material Science Precursor: Investigated for the development of organic semiconductors, conductive polymers, or non-linear optical (NLO) materials due to its π-conjugated system.
• Chemical Biology Probe: Utilized in research as a molecular tool to study enzyme inhibition or protein-ligand interactions.
• Academic & Institutional Research: A valuable compound for methodological studies and educational purposes in advanced organic chemistry laboratories.

Basic Information

Item	Details
Product Name	(2E)-N-(2-Cyanophenyl)-3-(Thiophen-2-yl)prop-2-enamide
CAS No.	658070-03-2
Molecular Formula	C14H10N2OS
Molecular Weight	254.31 g/mol
Synonyms	(E)-N-(2-Cyanophenyl)-3-(thiophen-2-yl)acrylamide; 2-Cyano-N-[(1E)-3-(2-thienyl)-1-propen-1-yl]benzenamine; (E)-2-Cyano-N-(3-(thiophen-2-yl)allyl)aniline; 658070-03-2; (2E)-3-(2-Thienyl)-N-(2-cyanophenyl)-2-propenamide; Acrylamide, N-(2-cyanophenyl)-3-(2-thienyl)-, (E)-; (E)-N-(2-Cyanophenyl)-3-(2-thienyl)acrylamide
EINECS	Contact for details

Quality Control

Our (2E)-N-(2-Cyanophenyl)-3-(Thiophen-2-yl)prop-2-enamide is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0% (Standard Grade)
Purity (HPLC)	≥ 98.5% (High Purity Grade)
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.