Description

Bicyclo[4.2.0]Octane-7-Methanol, 6-Hydroxy-, (1R,6S,7S)-Rel- (9Ci) is a high-purity, stereochemically defined bicyclic compound that serves as a critical chiral building block in advanced organic synthesis. Its unique fused ring structure and functional groups make it a valuable intermediate for constructing complex molecular architectures with precise three-dimensional control. This compound is primarily sought after by research institutions and pharmaceutical development teams for applications in medicinal chemistry, asymmetric catalysis, and the synthesis of novel bioactive molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in areas requiring rigid, polycyclic frameworks.
• Asymmetric Synthesis: Used as a precursor or ligand component in catalytic systems to induce chirality in target molecules.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and the construction of compound libraries for high-throughput screening.
• Fine Chemical Production: Serves as a specialized intermediate in the multi-step synthesis of complex fragrances, agrochemicals, and other high-value fine chemicals.
• Academic & Industrial R&D: A valuable tool for methodological development in organic synthesis and exploring new chemical spaces in material science.

Basic Information

Product Name	Bicyclo[4.2.0]Octane-7-Methanol, 6-Hydroxy-, (1R,6S,7S)-Rel- (9Ci)
CAS No.	657428-66-5
Molecular Formula	C9H16O2
Molecular Weight	156.22 g/mol
Synonyms	(1R,6S,7S)-rel-6-Hydroxybicyclo[4.2.0]octane-7-methanol; rel-(1R,6S,7S)-Bicyclo[4.2.0]octane-7-methanol, 6-hydroxy-; Bicyclo[4.2.0]octane-7-methanol, 6-hydroxy-, (1R,6S,7S)-rel-; 657428-66-5; Chiral Bicyclo[4.2.0]octane Derivative; Bicyclic Alcohol Intermediate
EINECS	Contact for details

Quality Control

Our production of Bicyclo[4.2.0]Octane-7-Methanol, 6-Hydroxy-, (1R,6S,7S)-Rel- (9Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is characterized using advanced analytical techniques, including chiral HPLC, NMR, and GC/MS, to confirm identity, stereochemical purity, and impurity profile. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.