Description

Bicyclo[4.2.0]Octane-7-Methanol, 6-Hydroxy-, (1R,6S,7R)-Rel- (9Ci) is a high-purity, stereochemically defined bicyclic compound that serves as a critical chiral building block and advanced pharmaceutical intermediate. Its unique fused ring structure and functional groups make it valuable for constructing complex molecular architectures with precise three-dimensional control. This compound is primarily sought by research institutions and manufacturers in the pharmaceutical and fine chemical sectors for applications in drug discovery, process development, and the synthesis of bioactive molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-infective drugs.
• Asymmetric Synthesis: Utilized as a sophisticated starting material or reagent in stereoselective organic synthesis to introduce complex bicyclic motifs.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization campaigns to explore novel chemical space.
• Process Chemistry: Serves as a benchmark or reference standard in the development and scaling of efficient synthetic routes for target molecules.
• Fine Chemical Production: Used in the manufacture of specialty chemicals, agrochemicals, and high-value performance materials requiring specific stereochemistry.
• Academic Research: A valuable compound for methodological studies in organic chemistry, catalysis, and the development of new synthetic transformations.

Basic Information

Product Name	Bicyclo[4.2.0]Octane-7-Methanol, 6-Hydroxy-, (1R,6S,7R)-Rel- (9Ci)
CAS No.	657428-65-4
Molecular Formula	C9H16O2
Molecular Weight	156.22 g/mol
Synonyms	(1R,6S,7R)-6-Hydroxybicyclo[4.2.0]octane-7-methanol; rel-(1R,6S,7R)-Bicyclo[4.2.0]octane-7-methanol, 6-hydroxy-; Bicyclo[4.2.0]octane-7-methanol, 6-hydroxy-, (1R,6S,7R)-rel-; 657428-65-4; Chiral Bicyclo[4.2.0]octane Derivative; Hydroxymethyl Bicyclo[4.2.0]octanol
EINECS	Contact for details

Quality Control

Our Bicyclo[4.2.0]Octane-7-Methanol, 6-Hydroxy-, (1R,6S,7R)-Rel- (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for research and pharmaceutical applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). For long-term storage, consider holding under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.