Description

4-(4-Ethylpiperazin-1-yl)phenylboronic acid is a specialized boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its value lies in its dual functionality, combining a reactive boronic acid group with a substituted piperazine moiety, making it an essential reagent for constructing complex molecular architectures. This compound is primarily needed by researchers and process chemists in the pharmaceutical and agrochemical industries for applications such as Suzuki-Miyaura cross-coupling reactions and medicinal chemistry programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting neurological and oncological pathways.
• Suzuki-Miyaura Cross-Coupling: Serves as a versatile boronic acid coupling partner for the formation of carbon-carbon bonds, essential for creating biaryl structures in drug discovery.
• Medicinal Chemistry & Drug Discovery: Used in high-throughput screening and library synthesis to explore structure-activity relationships (SAR) and develop new lead compounds.
• Agrochemical Synthesis: Employed in the development of novel herbicides, fungicides, and insecticides that require complex aromatic heterocycles.
• Material Science Research: Investigated as a monomer or functionalizing agent for advanced polymers and organic electronic materials.
• Chemical Biology Probes: Utilized to create tagged molecules for studying biological processes and protein-ligand interactions.

Basic Information

Product Name	4-(4-Ethylpiperazin-1-yl)phenylboronic Acid
CAS No.	657398-70-4
Molecular Formula	C12H19BN2O2
Molecular Weight	234.11 g/mol
Synonyms	4-(4-Ethyl-1-piperazinyl)benzeneboronic Acid; [4-(4-Ethylpiperazin-1-yl)phenyl]boronic Acid; B-[4-(4-Ethyl-1-piperazinyl)phenyl]boronic Acid; 4-(4-Ethylpiperazino)phenylboronic Acid; 4-(N-Ethylpiperazino)phenylboronic Acid; 657398-70-4; 4-(4-Ethylpiperazin-1-yl)benzeneboronic Acid
EINECS	Contact for details

Quality Control

Our 4-(4-Ethylpiperazin-1-yl)phenylboronic acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available upon request to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.