Description

n-(Tetrahydro-2H-Pyran-4-Yl)-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzamide is a high-purity boronic ester derivative, a crucial building block in modern synthetic organic chemistry. Its value lies in enabling efficient carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex molecules. This advanced intermediate is essential for researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries developing novel active compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly for small molecule therapeutics.
• Agrochemical Research: Used in constructing novel herbicides, fungicides, and insecticides through palladium-catalyzed coupling reactions.
• Material Science: Serves as a monomer or functionalization agent in the development of organic electronic materials, such as polymers for OLEDs or OFETs.
• Chemical Biology & Probe Development: Employed in creating bioconjugates and molecular probes for diagnostic and research applications.
• Catalyst & Ligand Synthesis: A versatile starting material for synthesizing complex ligands and organometallic catalysts.
• Custom Synthesis & Contract Manufacturing: A critical component for CROs and CDMOs offering bespoke chemical synthesis services.

Basic Information

Product Name	n-(Tetrahydro-2H-Pyran-4-Yl)-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzamide
CAS No.	656239-37-1
Molecular Formula	C18H26BNO4
Molecular Weight	331.22 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-N-(tetrahydro-2H-pyran-4-yl)benzamide; 4-(Tetramethyl-1,3,2-dioxaborolan-2-yl)-N-(oxan-4-yl)benzamide; Benzamide, N-(tetrahydro-2H-pyran-4-yl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 656239-37-1; 4-Pinacolatoboron-N-tetrahydropyran-4-yl-benzamide; N-(Oxan-4-yl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide
EINECS	Contact for details

Quality Control

Our n-(Tetrahydro-2H-Pyran-4-Yl)-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee batch-to-batch consistency and traceability for your R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.