Description

5-(1H-Pyrazol-3-Yl)-2-Thiophenecarboxylic Acid is a high-purity heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a versatile intermediate for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and material science sectors for creating novel compounds with targeted properties.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in kinase inhibitor and other small-molecule therapeutic programs.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides that require specific heterocyclic motifs for bioactivity.
• Material Science Research: Serves as a precursor for organic electronic materials, such as organic semiconductors and conductive polymers, due to its fused thiophene-pyrazole structure.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and protein interactions.
• Ligand Synthesis for Catalysis: Useful for constructing complex chelating ligands used in homogeneous catalysis and metal-organic frameworks (MOFs).
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Product Name	5-(1H-Pyrazol-3-Yl)-2-Thiophenecarboxylic Acid
CAS No.	656226-63-0
Molecular Formula	C8H6N2O2S
Molecular Weight	194.21 g/mol
Synonyms	5-(1H-Pyrazol-3-yl)thiophene-2-carboxylic acid; 2-Thiophenecarboxylic acid, 5-(1H-pyrazol-3-yl)-; 5-(1H-Pyrazol-3-yl)-2-thiophenecarboxylic acid; 5-(1H-Pyrazol-3-yl)thiophene-2-carboxylate; 3-(2-Carboxythiophen-5-yl)-1H-pyrazole; 5-(1H-Pyrazol-3-yl)thiophene-2-carboxylic acid (656226-63-0)
EINECS	Contact for details

Quality Control

Our 5-(1H-Pyrazol-3-Yl)-2-Thiophenecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) with detailed specifications are available for every shipment upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.