Description

7-Methoxy-1-Methyl-D-Tryptophan Ethyl Ester is a specialized, non-natural tryptophan derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical chiral building block and intermediate for the synthesis of complex molecules, particularly in the field of drug discovery. It is primarily utilized by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in developing novel therapeutic agents, including enzyme inhibitors and receptor modulators.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in neurological and metabolic disorder pathways.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies and proteomics research to investigate biological mechanisms.
• Peptidomimetics & Drug Design: Serves as a constrained tryptophan analog for constructing peptide-like molecules with enhanced stability and bioavailability.
• Asymmetric Synthesis: Employed as a starting material or intermediate in stereoselective chemical synthesis due to its defined D-configuration and methoxy substitution.
• Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation in pharmaceutical analysis.

Basic Information

Product Name	7-Methoxy-1-Methyl-D-Tryptophan Ethyl Ester
CAS No.	655239-35-3
Molecular Formula	C₁₅H₂₀N₂O₃
Molecular Weight	276.33 g/mol
Synonyms	D-1-Methyl-7-methoxytryptophan ethyl ester; Ethyl (2R)-2-amino-3-(1-methyl-7-methoxy-1H-indol-3-yl)propanoate; 7-Methoxy-1-methyl-D-abrine ethyl ester; (R)-Ethyl 2-amino-3-(1-methyl-7-methoxy-1H-indol-3-yl)propanoate; 1-Methyl-7-methoxy-D-tryptophan ethyl ester; D-7-Methoxy-1-methyltryptophan ethyl ester; 7-MeO-1-Me-D-Trp-OEt
EINECS	Contact for details

Quality Control

Our 7-Methoxy-1-Methyl-D-Tryptophan Ethyl Ester is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure high chemical and enantiomeric purity suitable for research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Chiral Purity (HPLC)	≥98.0% ee
Loss on Drying	≤1.0%
Residue on Ignition	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.