Description

4-Fluoro-2-Nitrobenzenethiol, also known as 4-Fluoro-2-Nitrophenyl Mercaptan, is a versatile aromatic thiol building block characterized by its nitro and fluorine substituents. This compound is essential for advanced organic synthesis, particularly in the construction of complex heterocycles and functional materials. It is primarily sought after by researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel active ingredients and ligands.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, especially those containing benzothiazole or other sulfur-heterocycle scaffolds.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides where the fluorine and nitro groups confer specific biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating novel sulfur-containing ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the development of organic electronic materials, dyes, and polymers due to its electron-withdrawing substituents.
• Chemical Biology Probes: Useful for synthesizing probes and inhibitors that target thiol-reactive enzymes or proteins.
• Custom Synthesis and R&D: A valuable building block for contract research organizations and academic laboratories exploring new chemical entities and reaction pathways.

Basic Information

Product Name	4-Fluoro-2-Nitrobenzenethiol
CAS No.	654063-68-0
Molecular Formula	C6H4FNO2S
Molecular Weight	173.16 g/mol
Synonyms	4-Fluoro-2-Nitrophenyl Mercaptan; 4-Fluoro-2-Nitrobenzenethiol; 2-Nitro-4-fluorobenzenethiol; 4-Fluoro-2-nitrothiophenol; 1-Fluoro-4-mercapto-3-nitrobenzene; 2-Nitro-4-fluorothiophenol; 4-Fluoro-2-nitro-1-benzenethiol; 654063-68-0
EINECS	Contact for details

Quality Control

Our 4-Fluoro-2-Nitrobenzenethiol is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical parameters. Our quality systems are designed to support cGMP and ISO standards for reliable supply to regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended long-term storage temperature is 2-8°C. This material is easily oxidized and moisture-sensitive; ensure containers are sealed immediately after use to minimize exposure to air and humidity.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.