Description

1H-Benzimidazole,1-(Trifluoromethyl)-(9Ci) is a specialized benzimidazole derivative distinguished by the presence of a trifluoromethyl substituent. This compound is a high-value pharmaceutical intermediate and building block for advanced organic synthesis, prized for its ability to impart unique physicochemical properties to target molecules. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and anti-inflammatory drug discovery programs.
• Agrochemical Synthesis: Used in the development of advanced fungicides, herbicides, and pesticides, where the benzimidazole core and fluorine atoms enhance biological activity and stability.
• Material Science Research: Serves as a precursor for organic ligands, catalysts, and functional polymers, contributing to the development of advanced materials with specific electronic or optical properties.
• Chemical Biology Probe: Employed in the design and synthesis of molecular probes and inhibitors for studying enzyme function and biological pathways.
• Organic Electronics: Potential monomer or dopant in the research of organic semiconductors and light-emitting materials due to its conjugated structure.

Basic Information

Product Name	1H-Benzimidazole,1-(Trifluoromethyl)-(9Ci)
CAS No.	652968-46-2
Molecular Formula	C8H5F3N2
Molecular Weight	186.14 g/mol
Synonyms	1-(Trifluoromethyl)-1H-benzimidazole; 1-(Trifluoromethyl)benzimidazole; 1-Trifluoromethylbenzimidazole; 1H-Benzimidazole, 1-(trifluoromethyl)-; Benzimidazole, 1-(trifluoromethyl)-; 652968-46-2
EINECS	Contact for details

Quality Control

Our 1-(Trifluoromethyl)-1H-benzimidazole is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the original container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.