Description

5-Bromopyridine-2-Boronic Acid Pinacol Ester is a high-value organoboron building block, specifically a protected boronic acid derivative, essential for modern cross-coupling chemistry. Its core value lies in enabling the precise and efficient construction of complex heterocyclic systems, which are pivotal in advanced material and pharmaceutical research. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for synthesizing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key reagent in Suzuki-Miyaura cross-coupling reactions for the synthesis of novel drug candidates, particularly those containing bipyridine or related heterocyclic scaffolds.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the introduction of specific halogenated pyridine motifs is required for bioactivity.
• Material Science Research: Serves as a building block for creating organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic light-emitting diodes (OLEDs).
• Chemical Biology Probes: Employed in the synthesis of molecular probes and tags for studying biological processes, leveraging the versatility of the boronic ester group for further functionalization.
• Catalyst Ligand Precursor: Acts as a precursor for synthesizing specialized ligands used in homogeneous catalysis.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	5-Bromopyridine-2-Boronic Acid Pinacol Ester
CAS No.	652148-98-6
Molecular Formula	C11H15BBrNO2
Molecular Weight	284.0 g/mol
Synonyms	5-Bromo-2-pyridineboronic acid pinacol ester; 2-(5-Bromopyridin-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; (5-Bromopyridin-2-yl)boronic acid pinacol ester; 5-Bromo-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 5-Bromopyridine-2-boronic acid neopentyl glycol ester (common alternative); Pinacol 5-bromopyridine-2-boronate; 652148-98-6; 5-Bromo-2-pyridylboronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 5-Bromopyridine-2-Boronic Acid Pinacol Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, meeting the stringent requirements of research and process chemistry. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant quality management standards to guarantee reliable supply and product integrity for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The container should be kept tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Melting Point	Contact for details
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.