Description

1H-Indazole, 6-Bromo-3-(Methylsulfonyl)- is a high-purity, advanced pharmaceutical intermediate characterized by its brominated indazole core and methylsulfonyl functional group. This compound is of significant commercial importance for its role as a key building block in the synthesis of novel, biologically active molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly in oncology and central nervous system (CNS) drug discovery.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of potential drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used extensively in structure-activity relationship (SAR) studies and lead optimization processes to develop new chemical entities.
• Kinase Inhibitor Development: Its structural features make it a valuable scaffold for the research and development of protein kinase inhibitors.
• Biochemical Tool Compound: Employed in biochemical assays and as a reference standard in pharmacological research.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.
• Academic Research: Utilized in university and institutional labs for fundamental organic chemistry and drug discovery projects.

Basic Information

Product Name	1H-Indazole, 6-Bromo-3-(Methylsulfonyl)-
CAS No.	651780-43-7
Molecular Formula	C8H7BrN2O2S
Molecular Weight	275.12 g/mol
Synonyms	6-Bromo-3-(methylsulfonyl)-1H-indazole; 6-Bromo-3-methanesulfonyl-1H-indazole; 3-Methanesulfonyl-6-bromo-1H-indazole; 1H-Indazole-3-sulfonic acid, 6-bromo-, methyl ester; 651780-43-7; 6-Bromo-3-methylsulfonylindazole; 6-Bromo-1H-indazole-3-sulfonic acid methyl ester
EINECS	Contact for details

Quality Control

Our 1H-Indazole, 6-Bromo-3-(Methylsulfonyl)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment aligns with the standards expected for pharmaceutical research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). The product should be kept under inert conditions if long-term stability is required. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.