Description

1H-Pyrrolo[2,3-b]pyridin-5-amine, 4-fluoro- (9CI) is a high-value, fluorinated heterocyclic building block of significant interest in modern organic synthesis. This compound matters because it provides a versatile core scaffold for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily needed by research chemists and process development scientists working on the discovery and optimization of new active ingredients, where its unique pyrrolopyridine structure offers a strategic advantage for modulating biological activity and physicochemical properties.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, especially kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic framework.
• Chemical Biology Probe Synthesis: Employed to create tool compounds for studying biological pathways and target validation.
• Material Science Research: Investigated as a building block for advanced organic electronic materials due to its conjugated system.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds for client R&D programs.
• Academic Research: Utilized in universities and research institutes for methodological studies in heterocyclic and fluorine chemistry.

Basic Information

Product Name	1H-Pyrrolo[2,3-b]pyridin-5-amine, 4-fluoro- (9CI)
CAS No.	651744-35-3
Molecular Formula	C7H6FN3
Molecular Weight	151.14 g/mol
Synonyms	4-Fluoro-1H-pyrrolo[2,3-b]pyridin-5-amine; 4-Fluoro-5-amino-7-azaindole; 4-Fluoro-7-azaindol-5-amine; 5-Amino-4-fluoro-1H-pyrrolo[2,3-b]pyridine; 4-Fluoro-1H-pyrrolo[2,3-b]pyridin-5-ylamine; 651744-35-3; 4-Fluoro-5-amino-1H-pyrrolo[2,3-b]pyridine
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[2,3-b]pyridin-5-amine, 4-fluoro- (9CI) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports your R&D and scale-up activities with reliable, traceable materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to protect from moisture and contamination. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.