Description

Carbamic Acid, [2-[(5-Isoquinolinylsulfonyl)Amino]Ethyl]-, 1,1-Dimethylethyl Ester (9Ci) is a specialized synthetic organic compound belonging to the class of carbamate-protected isoquinoline sulfonamide derivatives. This high-purity intermediate is of significant value for its role in advanced pharmaceutical research and fine chemical synthesis. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and life science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, particularly those targeting enzyme inhibition pathways.
• Protease Inhibitor Research: Used in the development and study of protease inhibitors due to the sulfonamide moiety's affinity for enzyme active sites.
• Kinase Inhibitor Scaffold: Acts as a key precursor in the creation of compounds designed to modulate kinase activity for therapeutic applications.
• Chemical Biology Probes: Employed in the design of activity-based probes (ABPs) for studying protein function and interaction within biological systems.
• Agrochemical Synthesis: Utilized as an advanced intermediate in the research and development of new-generation pesticides and herbicides.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-fidelity, protected intermediates.

Basic Information

Product Name	Carbamic Acid, [2-[(5-Isoquinolinylsulfonyl)Amino]Ethyl]-, 1,1-Dimethylethyl Ester (9Ci)
CAS No.	651309-72-7
Molecular Formula	C₁₆H₂₁N₃O₄S
Molecular Weight	351.42 g/mol
Synonyms	tert-Butyl N-[2-[(isoquinolin-5-ylsulfonyl)amino]ethyl]carbamate; N-[(1,1-Dimethylethoxy)carbonyl]-N'-(5-isoquinolinylsulfonyl)-1,2-ethanediamine; Boc-NH-(CH2)2-NH-SO2-Isoquinoline-5-yl; 5-Isoquinolinesulfonamide, N-[2-[[(1,1-dimethylethoxy)carbonyl]amino]ethyl]-; Boc-EDA-isoquinoline-5-sulfonamide; t-Butyl (2-((5-isoquinolinesulfonamido)ethyl)carbamate
EINECS	Contact for details

Quality Control

Our production of Carbamic Acid, [2-[(5-Isoquinolinylsulfonyl)Amino]Ethyl]-, 1,1-Dimethylethyl Ester (9Ci) adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all critical quality attributes are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound is stable under inert atmosphere but may degrade upon prolonged exposure to strong acids or organic solvents. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.