Description

N1-(4-Bromo-3-Cyclopropyl-1-Phenyl-1H-Pyrazol-5-Yl)-2-Chloroacetamide is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in research and development pipelines. It is primarily sought by pharmaceutical manufacturers and R&D organizations focused on developing new therapeutic agents, especially within medicinal chemistry programs targeting specific biological pathways.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of target drug candidates, particularly those with pyrazole-based core structures.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and the discovery of new bioactive molecules.
• API Development: Used in the process development and scale-up stages for potential new active pharmaceutical ingredients.
• Chemical Synthesis: Employed in organic synthesis for introducing the N-(2-chloroacetyl) functional group onto complex heterocycles.
• Agrochemical Research: Potential intermediate in the research and development of new crop protection agents with specific activity profiles.

Basic Information

Product Name	N1-(4-Bromo-3-Cyclopropyl-1-Phenyl-1H-Pyrazol-5-Yl)-2-Chloroacetamide
CAS No.	649701-48-4
Molecular Formula	C₁₄H₁₃BrClN₃O
Molecular Weight	354.63 g/mol
Synonyms	2-Chloro-N-(4-bromo-3-cyclopropyl-1-phenyl-1H-pyrazol-5-yl)acetamide; 2-Chloro-N-(4-bromo-3-cyclopropyl-1-phenylpyrazol-5-yl)acetamide; 649701-48-4; N-(4-Bromo-3-cyclopropyl-1-phenyl-1H-pyrazol-5-yl)-2-chloroacetamide; Acetamide, 2-chloro-N-(4-bromo-3-cyclopropyl-1-phenyl-1H-pyrazol-5-yl)-; 2-Chloro-N-(4-bromo-3-cyclopropyl-1-phenyl-1H-pyrazol-5-yl)ethanamide
EINECS	Contact for details

Quality Control

Our N1-(4-Bromo-3-Cyclopropyl-1-Phenyl-1H-Pyrazol-5-Yl)-2-Chloroacetamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and production. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents. For long-term storage, consider conditions under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.