Description

Methyl 5-(4-Chlorophenyl)Thiophene-2-Carboxylate is a high-purity, synthetically valuable organic building block, specifically a thiophene-based ester derivative. This compound is essential for advanced research and development in medicinal chemistry and material science, serving as a critical intermediate for constructing complex molecular architectures. It is primarily sought after by pharmaceutical R&D teams, agrochemical innovators, and specialty chemical manufacturers for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Research: Used in developing novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the thiophene and chlorophenyl motifs.
• Material Science: Serves as a monomer or building block for creating conjugated polymers and organic semiconductors for electronic applications.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Stille) to introduce the functionalized thiophene moiety into more complex molecules.
• Ligand & Catalyst Development: Utilized to synthesize novel chelating ligands for metal catalysts used in asymmetric synthesis.
• Academic & Industrial R&D: A standard reagent for methodological studies and exploring new synthetic pathways in heterocyclic chemistry.

Basic Information

Product Name	Methyl 5-(4-Chlorophenyl)Thiophene-2-Carboxylate
CAS No.	649569-56-2
Molecular Formula	C12H9ClO2S
Molecular Weight	252.71 g/mol
Synonyms	Methyl 5-(p-Chlorophenyl)thiophene-2-carboxylate; 5-(4-Chlorophenyl)thiophene-2-carboxylic acid methyl ester; 2-Thiophenecarboxylic acid, 5-(4-chlorophenyl)-, methyl ester; Methyl 5-(4'-chlorophenyl)thiophene-2-carboxylate; p-Chlorophenyl thiophene carboxylate methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 5-(4-Chlorophenyl)Thiophene-2-Carboxylate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and current industry standards for research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.