Description

6-(5-Acetylthiophen-2-Yl)-Nicotinic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its unique heterocyclic structure combining nicotinic acid and acetylthiophene moieties. This compound is critical for the research and development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for synthesis and scale-up activities.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with specific activity profiles.
• Material Science: Serves as a precursor for organic electronic materials, such as organic semiconductors or conductive polymers.
• Chemical Biology: Employed as a molecular probe or linker in bioconjugation and proteomics research.
• Academic & Contract Research: Essential for synthetic organic chemistry research in academic institutions and CROs (Contract Research Organizations).
• Custom Synthesis: Foundation for the custom manufacturing of complex, specialty molecules for client-specific applications.

Basic Information

Product Name	6-(5-Acetylthiophen-2-Yl)-Nicotinic Acid
CAS No.	649557-64-2
Molecular Formula	C13H9NO3S
Molecular Weight	259.28 g/mol
Synonyms	6-(5-Acetyl-2-thienyl)nicotinic acid; 6-(5-Acetylthiophen-2-yl)pyridine-3-carboxylic acid; 3-Pyridinecarboxylic acid, 6-(5-acetyl-2-thienyl)-; 5-Acetyl-2-thiophenenictonic acid; 6-(5-Acetyl-2-thienyl)-3-pyridinecarboxylic acid; 649557-64-2; Nicotinic acid, 6-(5-acetyl-2-thienyl)-
EINECS	Contact for details

Quality Control

Our 6-(5-Acetylthiophen-2-Yl)-Nicotinic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider the use of desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.