Description

1H-Indole-2-Carbonitrile, 4,6-Dichloro- is a high-purity, halogenated indole derivative serving as a critical synthetic intermediate. This compound is valued for its versatile reactivity, particularly in constructing complex heterocyclic scaffolds essential for modern drug discovery. It is primarily sought by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. Its specific substitution pattern makes it a key building block for medicinal chemistry programs targeting a range of therapeutic areas.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those with indole-based core structures for oncology, CNS, and anti-infective applications.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators, leveraging its heterocyclic framework.
• Material Science: Serves as a monomer or functional unit in the research of advanced organic electronic materials and specialty polymers.
• Chemical Synthesis: Employed in academic and industrial R&D for constructing complex nitrogen-containing heterocycles via cross-coupling, cyclization, and functional group transformation reactions.
• Biochemical Tool Compound: Potential use in developing probes and inhibitors for studying enzymatic pathways and biological targets.

Basic Information

Product Name	1H-Indole-2-Carbonitrile, 4,6-Dichloro-
CAS No.	648417-02-1
Molecular Formula	C9H4Cl2N2
Molecular Weight	211.05 g/mol
Synonyms	4,6-Dichloro-1H-indole-2-carbonitrile; 4,6-Dichloroindole-2-carbonitrile; 2-Cyano-4,6-dichloroindole; 4,6-Dichloro-2-cyanoindole; 1H-Indole-2-carbonitrile, 4,6-dichloro-; 648417-02-1; 4,6-Dichloro-1H-indole-2-carbonitrile
EINECS	Contact for details

Quality Control

Our 1H-Indole-2-Carbonitrile, 4,6-Dichloro- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to traceability and documentation supports our clients' regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.