Description

Methyl 4-Bromo-5-Cyano-3-Methylthiophene-2-Carboxylate is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound matters because its unique molecular architecture, featuring bromo, cyano, and ester functionalities on a thiophene core, makes it a versatile precursor for constructing complex molecules. It is critically needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Serves as a building block for creating advanced herbicides, fungicides, and insecticides with tailored properties.
• Material Science: Used in the synthesis of functionalized thiophene-based polymers and organic semiconductors for electronic applications.
• Chemical Research: Employed in academic and industrial R&D for exploring new heterocyclic chemistry and cross-coupling reactions (e.g., Suzuki, Stille).
• Ligand and Catalyst Development: Acts as a precursor for synthesizing specialized ligands used in catalytic systems.
• Dye and Pigment Intermediate: Utilized in the production of specialized colorants and imaging agents.

Basic Information

Product Name	Methyl 4-Bromo-5-Cyano-3-Methylthiophene-2-Carboxylate
CAS No.	648412-55-9
Molecular Formula	C8H6BrNO2S
Molecular Weight	260.11 g/mol
Synonyms	Methyl 4-bromo-5-cyano-3-methylthiophene-2-carboxylate; 4-Bromo-5-cyano-3-methylthiophene-2-carboxylic acid methyl ester; 2-Thiophenecarboxylic acid, 4-bromo-5-cyano-3-methyl-, methyl ester; Methyl 4-bromo-5-cyano-3-methyl-2-thiophenecarboxylate; 648412-55-9; Methyl 4-bromo-5-cyano-3-methylthiophene-2-carboxylate (CAS 648412-55-9)
EINECS	Contact for details

Quality Control

Our Methyl 4-Bromo-5-Cyano-3-Methylthiophene-2-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our commitment to quality supports your R&D and scale-up processes with reliable, high-purity material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is moisture-sensitive; ensure containers are sealed to prevent exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.