Description

N2-Phenyl-4-(2-Chloro-5-Nitrophenyl)-1,3-Thiazol-2-Amine Hydrobromide is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in research and development pipelines. It is primarily sought by pharmaceutical manufacturers and contract research organizations (CROs) engaged in developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting specific biological pathways.
• Research & Development (R&D): Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a core structural component in the multi-step manufacturing process of complex APIs.
• Chemical Biology Probes: Can be utilized in the development of molecular probes for studying enzyme function or receptor interactions in biological systems.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	N2-Phenyl-4-(2-Chloro-5-Nitrophenyl)-1,3-Thiazol-2-Amine Hydrobromide
CAS No.	648409-23-8
Molecular Formula	C15H11BrClN3O2S
Molecular Weight	412.69 g/mol
Synonyms	2-[(2-Chloro-5-nitrophenyl)-4-thiazolyl]amino-N-phenylbenzamide hydrobromide; 4-(2-Chloro-5-nitrophenyl)-N-phenyl-1,3-thiazol-2-amine hydrobromide; N-Phenyl-4-(2-chloro-5-nitrophenyl)thiazol-2-amine HBr; 648409-23-8; Thiazole derivative hydrobromide salt; Pharmaceutical intermediate 648409-23-8
EINECS	Contact for details

Quality Control

Our N2-Phenyl-4-(2-Chloro-5-Nitrophenyl)-1,3-Thiazol-2-Amine Hydrobromide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting comprehensive HPLC purity, related substances, and residual solvent levels are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Loss on Drying	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.