Description

4-Benzyloxy-1-Bromo-2-Trifluoromethoxybenzene is a high-purity, multi-functional aromatic building block designed for advanced synthetic chemistry. This compound is valued for its unique combination of halogen and ether substituents, which enable precise molecular modifications in complex organic syntheses. It serves as a critical intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, where reliable quality and structural specificity are paramount.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting novel small molecules.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, leveraging its halogenated aromatic structure.
• Liquid Crystal & OLED Material Precursor: Serves as a specialized intermediate in the production of fluorinated organic compounds for electronic display and lighting applications.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Heck, and Buchwald-Hartwig amination due to the reactive bromine atom.
• Organic Synthesis Research: A versatile reagent in academic and industrial R&D labs for constructing complex, poly-substituted benzene derivatives.
• Fluorine Chemistry Studies: Used as a model compound in developing new methodologies for introducing and manipulating trifluoromethoxy groups.

Basic Information

Product Name	4-Benzyloxy-1-Bromo-2-Trifluoromethoxybenzene
CAS No.	647856-28-8
Molecular Formula	C14H10BrF3O2
Molecular Weight	347.13 g/mol
Synonyms	1-Bromo-4-(benzyloxy)-2-(trifluoromethoxy)benzene; 2-Trifluoromethoxy-4-benzyloxy-1-bromobenzene; 4-Benzyloxy-2-trifluoromethoxy-1-bromobenzene; 1-Bromo-2-trifluoromethoxy-4-benzyloxybenzene; Benzene, 1-bromo-4-(phenylmethoxy)-2-(trifluoromethoxy)-; 4-(Benzyloxy)-1-bromo-2-(trifluoromethoxy)benzene
EINECS	Contact for details

Quality Control

Every batch of 4-Benzyloxy-1-Bromo-2-Trifluoromethoxybenzene is manufactured and tested under a strict quality management system. We guarantee high chemical purity and structural integrity through comprehensive analytical techniques including HPLC, GC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to ensure traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.