Description

4,6-Dioxa-2-Azabicyclo[3.2.0]Hept-2-Ene,7-Ethyl-5-Methoxy-1,3-Dimethyl-,(1R,5S,7R)-Rel-(9Ci) is a high-purity, stereochemically defined bicyclic heterocyclic compound with the CAS number 647012-58-6. This advanced pharmaceutical intermediate is valued for its complex molecular architecture, which serves as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly within medicinal chemistry and process R&D.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of complex drug candidates, especially for central nervous system (CNS) and anti-infective therapies.
• Medicinal Chemistry Research: Used as a scaffold or precursor in structure-activity relationship (SAR) studies to explore new bioactive molecules.
• Process Chemistry Development: Serves as a critical intermediate for scaling up and optimizing synthetic routes under current Good Manufacturing Practice (cGMP) guidelines.
• Asymmetric Synthesis: Utilized in stereoselective reactions to construct molecules with specific three-dimensional configurations required for biological activity.
• Contract Research & Manufacturing (CRAM): Supplied to CDMOs for custom synthesis projects and pilot-scale production of novel compounds.
• Academic Research: Employed in university and institutional labs for methodological development in organic and heterocyclic chemistry.

Basic Information

Product Name	4,6-Dioxa-2-Azabicyclo[3.2.0]Hept-2-Ene,7-Ethyl-5-Methoxy-1,3-Dimethyl-,(1R,5S,7R)-Rel-(9Ci)
CAS No.	647012-58-6
Molecular Formula	C10H17NO3
Molecular Weight	199.25 g/mol
Synonyms	(1R,5S,7R)-rel-7-Ethyl-5-methoxy-1,3-dimethyl-4,6-dioxa-2-azabicyclo[3.2.0]hept-2-ene; 7-Ethyl-5-methoxy-1,3-dimethyl-4,6-dioxa-2-azabicyclo[3.2.0]hept-2-ene, (1R,5S,7R)-rel-; Bicyclic Oxazolidine Derivative; Advanced Pharmaceutical Intermediate 647012-58-6; (rel)-(1R,5S,7R)-7-Ethyl-5-methoxy-1,3-dimethyl-4,6-dioxa-2-azabicyclo[3.2.0]hept-2-ene
EINECS	Contact for details

Quality Control

Our 4,6-Dioxa-2-Azabicyclo[3.2.0]Hept-2-Ene,7-Ethyl-5-Methoxy-1,3-Dimethyl-,(1R,5S,7R)-Rel-(9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for research and development applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant quality management standards to guarantee reliable supply and traceability for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere such as nitrogen or argon to prevent degradation. Keep away from strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.