Description

Racemic-(4R,4Ar,8As)-Ethyl Decahydroisoquinoline-4-Carboxylate Acetate is a high-purity, advanced pharmaceutical intermediate with a complex, rigid polycyclic structure. This compound is valued for its role as a critical chiral building block in the synthesis of active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel therapeutic agents and complex organic molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel central nervous system (CNS) active drugs and other therapeutic compounds.
• Asymmetric Synthesis: Serves as a versatile building block for constructing complex molecular architectures with defined stereochemistry in medicinal chemistry.
• Agrochemical Research: Used in the development of new pesticides and herbicides that require specific stereoisomers for optimal biological activity.
• Catalyst and Ligand Development: Acts as a precursor for nitrogen-containing ligands used in asymmetric catalysis and transition metal complexes.
• Academic & Industrial R&D: Employed in chemical research for studying reaction mechanisms, stereochemistry, and the synthesis of natural product analogs.
• Fine Chemical Production: Utilized in the multi-step synthesis of high-value, low-volume specialty chemicals for various industrial applications.

Basic Information

Product Name	Racemic-(4R,4Ar,8As)-Ethyl Decahydroisoquinoline-4-Carboxylate Acetate
CAS No.	646518-35-6
Molecular Formula	C14H23NO4
Molecular Weight	269.34 g/mol
Synonyms	Ethyl (4R,4aR,8aS)-decahydroisoquinoline-4-carboxylate acetate; (±)-Ethyl Decahydroisoquinoline-4-Carboxylate Acetate; Ethyl 1,2,3,4,4a,5,6,7,8,8a-Decahydroisoquinoline-4-carboxylate Acetate; Decahydroisoquinoline-4-carboxylic Acid Ethyl Ester Acetate; (4R,4aR,8aS)-Ethyl Octahydro-1H-isoquinoline-4-carboxylate Acetate; 646518-35-6; UNII-Contact for details
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for pharmaceutical intermediates. Each batch is characterized and controlled using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to confirm identity, purity, and stereochemical integrity. Certificates of Analysis (COA) detailing all relevant specifications are available upon request. We adhere to cGMP principles where applicable to support our global clientele in regulated markets.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.