Description

2-Aminofluorobenzene-3,4,5,6-D4 is a deuterium-labeled derivative of 2-fluoroaniline, a key building block in advanced chemical synthesis. This isotopically labeled compound is essential for creating internal standards and labeled tracers used in quantitative mass spectrometry and metabolic studies. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and analytical chemistry sectors who require high-purity, stable-labeled compounds for precise analytical and developmental work.

Application

• Internal Standard for Mass Spectrometry (MS): Serves as a critical quantitative reference standard in LC-MS and GC-MS analysis for pharmacokinetic and bioanalytical studies.
• Metabolic Pathway Tracing: Used in drug metabolism and disposition (DMPK) research to track the fate of molecules within biological systems.
• Pharmaceutical Intermediate: Acts as a deuterated synthon in the research and development of novel active pharmaceutical ingredients (APIs).
• Agrochemical Research: Employed in the development and environmental fate studies of new pesticides and herbicides.
• NMR Spectroscopy: Useful as a probe in nuclear magnetic resonance studies due to the absence of proton signals in the deuterated positions.
• Chemical Mechanism Elucidation: Aids in investigating reaction mechanisms and kinetics in synthetic organic chemistry.

Basic Information

Product Name	2-Aminofluorobenzene-3,4,5,6-D4
CAS No.	646502-91-2
Molecular Formula	C6H2D4FN
Molecular Weight	115.14 g/mol
Synonyms	2-Fluoroaniline-3,4,5,6-d4; 1-Amino-2-fluorobenzene-3,4,5,6-d4; 2-Fluoroaniline-d4; 2-Fluoro-1-aminobenzene-d4; o-Fluoroaniline-d4; Deuterated 2-Fluoroaniline; (2-Fluorophenyl)amine-d4; 2-Fluorobenzenamine-d4
EINECS	Contact for details

Quality Control

Every batch of 2-Aminofluorobenzene-3,4,5,6-D4 is produced and analyzed under strict quality management protocols to ensure exceptional isotopic and chemical purity. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing key parameters such as isotopic purity (D-enrichment), chemical purity by HPLC, and identity confirmation by spectroscopic methods.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, prolonged exposure to air and light should be avoided to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR / NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-enrichment)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.