Description

(3-Chlorothiophen-2-Yl)Methanamine Hydrochloride is a high-purity organic building block and pharmaceutical intermediate of significant commercial importance. Its core value lies in its functionalized thiophene scaffold, which is a privileged structure in medicinal chemistry for the development of novel active compounds. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors seeking to develop new molecules with targeted properties.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-infective research.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and insecticides that leverage the thiophene moiety for bioactivity.
• Material Science Research: Serves as a precursor for functionalized monomers in the creation of conductive polymers and organic electronic materials.
• Chemical Biology & Proteomics: Employed as a specialty reagent for labeling and modifying biomolecules in probe development.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for clients.
• Academic & R&D Laboratories: Used in university and industrial research settings for method development and exploring new chemical spaces in heterocyclic chemistry.

Basic Information

Product Name	(3-Chlorothiophen-2-Yl)Methanamine Hydrochloride
CAS No.	643088-03-3
Molecular Formula	C5H7Cl2NS
Molecular Weight	184.09 g/mol
Synonyms	1-(3-Chlorothiophen-2-yl)methanamine hydrochloride; (3-Chloro-2-thienyl)methanamine hydrochloride; 2-(Aminomethyl)-3-chlorothiophene hydrochloride; 3-Chloro-2-thiophenemethylamine hydrochloride; 3-Chlorothiophene-2-methylamine hydrochloride; 3-Chloro-2-thienylmethylamine HCl; (3-Chloro-thiophen-2-yl)-methylamine hydrochloride
EINECS	Contact for details

Quality Control

Our (3-Chlorothiophen-2-Yl)Methanamine Hydrochloride is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.