Description

7-Nitro-1,2,3,4-Tetrahydro-9H-Pyrido[3,4-B]Indole is a high-purity, advanced pharmaceutical intermediate belonging to the β-carboline alkaloid class. This compound is valued for its complex heterocyclic structure, which serves as a critical building block in modern medicinal chemistry research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology sectors for the synthesis of novel active pharmaceutical ingredients (APIs) and for pharmacological screening.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting neurological and oncological pathways.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and the development of new β-carboline-based therapeutics.
• Biochemical Tool Compound: Employed in biochemical assays and as a reference standard to study enzyme inhibition and receptor binding activities.
• Organic Synthesis Building Block: Utilized in multi-step synthetic routes to construct more complex polycyclic or functionalized heterocyclic molecules.
• Academic & Industrial R&D: Serves as a vital material for exploratory research in universities, contract research organizations (CROs), and pharmaceutical R&D departments.

Basic Information

Product Name	7-Nitro-1,2,3,4-Tetrahydro-9H-Pyrido[3,4-B]Indole
CAS No.	642412-39-3
Molecular Formula	C₁₁H₁₁N₃O₂
Molecular Weight	217.23 g/mol
Synonyms	7-Nitro-1,2,3,4-tetrahydro-9H-pyrido[3,4-b]indole; 9H-Pyrido[3,4-b]indole, 1,2,3,4-tetrahydro-7-nitro-; 7-Nitro-1,2,3,4-tetrahydro-β-carboline; 7-Nitro-THBC; 7-Nitro-1,2,3,4-tetrahydro-β-carboline; 7-Nitro-tetrahydro-β-carboline; 7-Nitro-1,2,3,4-tetrahydro-9H-pyrido[3,4-b]indole
EINECS	Contact for details

Quality Control

Our 7-Nitro-1,2,3,4-Tetrahydro-9H-Pyrido[3,4-B]Indole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, long-term storage under an inert atmosphere (e.g., nitrogen or argon) is recommended for optimal stability. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.