Description

6-Bromo-3-(3H-Imidazol-4-Ylmethylene)-1,3-Dihydro-Indol-2-One is a specialized heterocyclic organic compound featuring a brominated indolinone core fused with an imidazole moiety. This unique molecular architecture makes it a valuable synthetic intermediate and building block in advanced pharmaceutical and agrochemical research. It is primarily utilized by R&D chemists and process development scientists in the life sciences sector for the synthesis of novel active compounds.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, particularly those targeting kinase inhibition or other enzyme-related pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or plant growth regulators due to its bioactive heterocyclic structure.
• Chemical Biology Probe: Acts as a scaffold or a tagged molecule for studying protein-ligand interactions and cellular processes.
• Material Science Research: Investigated as an organic component for advanced materials, such as organic semiconductors or photoresponsive polymers.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies and the exploration of new chemical reactions.

Basic Information

Product Name	6-Bromo-3-(3H-Imidazol-4-Ylmethylene)-1,3-Dihydro-Indol-2-One
CAS No.	638563-57-2
Molecular Formula	C12H8BrN3O
Molecular Weight	290.12 g/mol
Synonyms	6-Bromo-3-[(1H-imidazol-5-yl)methylene]-1,3-dihydro-2H-indol-2-one; 6-Bromo-3-(1H-imidazol-5-ylmethylene)indolin-2-one; 2H-Indol-2-one, 6-bromo-1,3-dihydro-3-[(1H-imidazol-5-yl)methylene]-; 6-Bromo-3-(imidazol-4-ylmethylene)indolin-2-one; 638563-57-2; BIIB 021 Impurity; HSP90 Inhibitor Intermediate
EINECS	Contact for details

Quality Control

Every batch of 6-Bromo-3-(3H-Imidazol-4-Ylmethylene)-1,3-Dihydro-Indol-2-One is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and consistency for your research and development needs. A detailed Certificate of Analysis (COA) with specifications for purity (typically by HPLC), identity confirmation (by IR, NMR), and impurity profile is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container sealed to protect this light-sensitive compound from degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.