Description

(E)-4-Bromo-3-Hydrazonoeindolin-2-One is a specialized brominated indolinone derivative featuring a hydrazone functional group, serving as a high-value synthetic intermediate. This compound matters for its role in constructing complex molecular architectures, particularly in the development of novel bioactive molecules. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for advanced synthesis and medicinal chemistry programs.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of kinase inhibitors and other targeted therapeutic agents.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR).
• Agrochemical Development: Intermediate for creating novel crop protection agents with specific modes of action.
• Chemical Biology Probes: Serves as a precursor for developing molecular probes to study enzyme function and biological pathways.
• Organic Synthesis: Versatile synthon for constructing fused heterocyclic systems and complex organic molecules.

Basic Information

Product Name	(E)-4-Bromo-3-Hydrazonoeindolin-2-One
CAS No.	638563-43-6
Molecular Formula	C8H6BrN3O
Molecular Weight	240.06 g/mol
Synonyms	4-Bromo-3-hydrozonylindolin-2-one; (E)-4-Bromo-3-hydrozonoindolin-2-one; 4-Bromo-3-hydrozonyl-2-indolinone; 2H-Indol-2-one, 4-bromo-1,3-dihydro-3-hydrozonyl-, (3E)-; 4-Bromo-3-hydrozonyl-1,3-dihydro-2H-indol-2-one; 638563-43-6; (E)-4-Bromo-3-hydrozonylindolin-2-one
EINECS	Contact for details

Quality Control

Our (E)-4-Bromo-3-Hydrazonoeindolin-2-One is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with full characterization data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C under an inert atmosphere, as the material is easily oxidized and light-sensitive. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.