Description

4,6-Dibromo-2-(4-Fluorophenyl)-1,3-Benzoxazol-5-Amine is a high-purity, halogenated benzoxazole derivative serving as a critical advanced intermediate in modern organic synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for lead optimization and scale-up activities. CAS number is provided in the table below.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging its halogenated structure for bioactivity.
• Material Science: Serves as a precursor for organic light-emitting diodes (OLEDs) and other electronic materials due to the benzoxazole core.
• Chemical Biology: Employed as a molecular probe or tag in biochemical research to study protein interactions and enzyme mechanisms.
• Academic & Contract Research: Essential for methodological development and synthetic chemistry studies in university and CRO laboratories.

Basic Information

Product Name	4,6-Dibromo-2-(4-Fluorophenyl)-1,3-Benzoxazol-5-Amine
CAS No.	637302-88-6
Molecular Formula	C₁₃H₇Br₂FN₂O
Molecular Weight	410.01 g/mol
Synonyms	5-Amino-4,6-dibromo-2-(4-fluorophenyl)benzoxazole; 2-(4-Fluorophenyl)-4,6-dibromo-1,3-benzoxazol-5-amine; 4,6-Dibromo-2-(p-fluorophenyl)benzoxazol-5-amine; DBFBA; 637302-88-6; Benzoxazole, 5-amino-4,6-dibromo-2-(4-fluorophenyl)-
EINECS	Contact for details

Quality Control

Our 4,6-Dibromo-2-(4-Fluorophenyl)-1,3-Benzoxazol-5-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high-purity intermediates for regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.