Description

1-n-Boc-5-Formyl-Indazole is a high-purity, multi-functional chemical building block essential for advanced organic synthesis. Its value lies in providing a protected indazole scaffold with a reactive aldehyde group, enabling precise and efficient construction of complex molecular architectures. This compound is critically needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for applications such as drug discovery and the synthesis of novel heterocyclic compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those targeting kinase inhibition and other biological pathways.
• Peptidomimetic & PROTAC Synthesis: Used to incorporate the indazole moiety into larger, bioactive molecules like peptide mimics and Proteolysis Targeting Chimeras (PROTACs).
• Agrochemical Research: Serves as a building block for developing novel herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science & Ligand Design: Employed in the creation of specialized ligands for catalysis and the development of advanced organic materials.
• Academic & Contract Research: A valuable reagent for method development and exploratory chemistry in university and CRO (Contract Research Organization) laboratories.
• Custom Synthesis & Scale-Up: Provides a reliable starting point for custom synthesis projects, from milligram-scale research to kilogram-scale process development.

Basic Information

Product Name	1-n-Boc-5-Formyl-Indazole
CAS No.	635713-71-2
Molecular Formula	C13H14N2O3
Molecular Weight	246.26 g/mol
Synonyms	1-[(tert-Butoxy)carbonyl]-1H-indazole-5-carboxaldehyde; 5-Formyl-1H-indazole-1-carboxylic acid tert-butyl ester; tert-Butyl 5-formyl-1H-indazole-1-carboxylate; 1-Boc-5-formylindazole; 1-(tert-Butoxycarbonyl)-5-formylindazole; Boc-5-formylindazole; 1H-Indazole-5-carboxaldehyde, 1-[(1,1-dimethylethoxy)carbonyl]-
EINECS	Contact for details

Quality Control

Our 1-n-Boc-5-Formyl-Indazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.