Description

(1S,1'S)-1,1',2,2',3,3',4,4'-Octahydro-1,1'-Biisoquinoline CAS NO 634180-45-3 is a high-purity, chiral bis-tetrahydroisoquinoline derivative. This compound serves as a sophisticated chiral building block and ligand precursor in advanced organic synthesis, valued for its rigid, three-dimensional structure. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of asymmetric catalysts and novel active pharmaceutical ingredients (APIs).

Application

• Asymmetric Catalysis: As a chiral ligand or ligand precursor in transition metal-catalyzed reactions such as hydrogenation, cross-coupling, and C-H activation.
• Pharmaceutical Intermediates: A key chiral scaffold in the synthesis of complex molecules for drug discovery and development programs.
• Organocatalysis: Potential use as an organocatalyst in enantioselective transformations.
• Material Science Research: As a building block for chiral polymers or frameworks with potential optical or electronic properties.
• Academic & Industrial R&D: For method development and exploration of new synthetic pathways in organic chemistry.

Basic Information

Product Name	(1S,1'S)-1,1',2,2',3,3',4,4'-Octahydro-1,1'-Biisoquinoline
CAS No.	634180-45-3
Molecular Formula	C20H24N2
Molecular Weight	292.42 g/mol
Synonyms	(1S,1'S)-Octahydro-1,1'-biisoquinoline; (S,S)-H8-BIQ; (1S,1'S)-H8-Biisoquinoline; (S,S)-1,1',2,2',3,3',4,4'-Octahydro-1,1'-biisoquinoline; (S,S)-Tetrahydro-BIQ; (S,S)-H8-BiQN; Chiral Biisoquinoline Ligand; (1S,1'S)-1,1',2,2',3,3',4,4'-Octahydro-1,1'-biquinoline
EINECS	Contact for details

Quality Control

Our (1S,1'S)-1,1',2,2',3,3',4,4'-Octahydro-1,1'-Biisoquinoline is produced under strict quality management systems. Each batch undergoes comprehensive analytical characterization, including chiral purity determination by HPLC, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Keep the container sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.