Description

Methyl 3-Amino-4-Chlorothiophene-2-Carboxylate is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound serves as a critical intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique thiophene core enables the construction of complex molecular architectures. It is primarily sought after by research and development chemists, process development teams, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing thiophene-based drug candidates, including potential kinase inhibitors, antiviral agents, and anti-inflammatory compounds.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that leverage the bioactivity of the chlorinated aminothiophene scaffold.
• Material Science Research: Serves as a precursor for functionalized monomers in the development of conductive polymers, organic semiconductors, and advanced organic electronic materials.
• Dye and Pigment Industry: Intermediate for creating specialized heterocyclic dyes and pigments with specific light-absorption properties.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in client-specific custom synthesis projects.

Basic Information

Product Name	Methyl 3-Amino-4-Chlorothiophene-2-Carboxylate
CAS No.	632356-41-3
Molecular Formula	C6H6ClNO2S
Molecular Weight	191.64 g/mol
Synonyms	Methyl 3-amino-4-chloro-2-thiophenecarboxylate; 3-Amino-4-chlorothiophene-2-carboxylic acid methyl ester; 4-Chloro-3-aminothiophene-2-carboxylic acid methyl ester; Methyl 4-chloro-3-aminothiophene-2-carboxylate; 2-Thiophenecarboxylic acid, 3-amino-4-chloro-, methyl ester; 3-Amino-4-chloro-2-methoxycarbonylthiophene
EINECS	Contact for details

Quality Control

Our Methyl 3-Amino-4-Chlorothiophene-2-Carboxylate is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our quality systems are designed to support development and commercial projects requiring reliable and traceable high-purity intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.