Description

Methyl 3-Acetamido-4-Chlorothiophene-2-Carboxylate is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound is valued for its role as a key intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily sought by research chemists and process development scientists working on novel active ingredients, including potential drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel thiophene-based drug candidates, including potential kinase inhibitors and anti-inflammatory agents.
• Agrochemical Research: Serves as a key building block for developing new generation herbicides, fungicides, and insecticides with improved efficacy.
• Material Science: Used in the research and development of specialty polymers and organic electronic materials due to its functionalized thiophene core.
• Chemical Synthesis: An advanced synthon for constructing complex heterocyclic frameworks in academic and industrial research laboratories.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific molecule production.

Basic Information

Product Name	Methyl 3-Acetamido-4-Chlorothiophene-2-Carboxylate
CAS No.	632356-40-2
Molecular Formula	C8H8ClNO3S
Molecular Weight	233.67 g/mol
Synonyms	Methyl 3-acetamido-4-chloro-2-thiophenecarboxylate; 3-Acetamido-4-chlorothiophene-2-carboxylic acid methyl ester; 4-Chloro-3-acetamidothiophene-2-carboxylic acid methyl ester; 2-Thiophenecarboxylic acid, 3-(acetylamino)-4-chloro-, methyl ester; Methyl 4-chloro-3-acetamidothiophene-2-carboxylate; 3-Acetylamino-4-chlorothiophene-2-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 3-Acetamido-4-Chlorothiophene-2-Carboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles as determined by advanced analytical techniques including HPLC, GC, and NMR. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents and strong bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.