Description

3-Acetylamino-4,5-Dichlorothiphene-2-Carboxylic Acid Methyl Ester is a high-purity, synthetically valuable heterocyclic building block. This compound is essential for advanced organic synthesis, serving as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and fungicides, leveraging its dichlorothiophene core.
• Material Science Research: Serves as a monomer or functionalization agent in the development of advanced polymers and organic electronic materials.
• Chemical Biology: Employed as a probe or linker in medicinal chemistry for structure-activity relationship (SAR) studies and bioconjugation.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	3-Acetylamino-4,5-Dichlorothiphene-2-Carboxylic Acid Methyl Ester
CAS No.	632356-39-9
Molecular Formula	C9H7Cl2NO3S
Molecular Weight	280.13 g/mol
Synonyms	Methyl 3-acetamido-4,5-dichlorothiophene-2-carboxylate; 4,5-Dichloro-3-acetylaminothiophene-2-carboxylic acid methyl ester; 3-Acetamido-4,5-dichlorothiophene-2-carboxylic acid methyl ester; 2-Thiophenecarboxylic acid, 3-(acetylamino)-4,5-dichloro-, methyl ester; Methyl 3-(acetylamino)-4,5-dichloro-2-thiophenecarboxylate; 3-Acetylamino-4,5-dichloro-thiophene-2-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our 3-Acetylamino-4,5-Dichlorothiphene-2-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency suitable for sensitive synthesis applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.