Description

(R)-1-(3-Chlorophenyl)-1,3-Propanediol CAS NO 632327-18-5 is a high-purity chiral diol intermediate of significant importance in asymmetric synthesis. Its value lies in its role as a key building block for the production of advanced pharmaceutical active ingredients and fine chemicals. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel therapeutic agents and high-value chiral molecules.

Application

• Pharmaceutical Intermediate: A critical chiral precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) drugs and other therapeutic agents requiring high stereochemical purity.
• Asymmetric Synthesis: Used as a chiral auxiliary or building block in stereoselective organic reactions to construct complex molecular architectures with defined three-dimensional configurations.
• Agrochemical Research: Serves as a starting material for developing novel chiral pesticides and herbicides, where the specific (R)-enantiomer can be essential for biological activity.
• Ligand and Catalyst Development: Employed in the preparation of chiral ligands for transition metal catalysts used in homogeneous catalysis and enantioselective transformations.
• Fine Chemical Production: Utilized in the manufacture of specialty chemicals, flavors, and fragrances that require enantiomerically pure components.
• Academic and R&D Laboratories: A valuable reagent for methodological development in organic chemistry and for probing structure-activity relationships in medicinal chemistry projects.

Basic Information

Product Name	(R)-1-(3-Chlorophenyl)-1,3-Propanediol
CAS No.	632327-18-5
Molecular Formula	C9H11ClO2
Molecular Weight	186.64 g/mol
Synonyms	(R)-1-(3-Chlorophenyl)propane-1,3-diol; (R)-3-Chloro-α-(hydroxymethyl)benzenemethanol; (R)-1-(3-Chlorophenyl)-1,3-dihydroxypropane; (R)-3-(3-Chlorophenyl)-3-hydroxy-1-propanol; (R)-3-Chlorophenyl-1,3-propanediol; (R)-enantiomer of 1-(3-Chlorophenyl)-1,3-propanediol; (R)-CPPD
EINECS	Contact for details

Quality Control

Our (R)-1-(3-Chlorophenyl)-1,3-Propanediol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with exacting standards for pharmaceutical and research applications. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.