Description

1-Chloro-6-(trifluoromethoxy)isoquinoline is a high-value, multi-functional heterocyclic building block. This compound is essential for advanced research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought after by pharmaceutical, agrochemical, and specialty chemical manufacturers for creating complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science Research: Serves as a precursor for functionalized polymers and organic electronic materials.
• Ligand and Catalyst Development: Employed in the design of novel ligands for transition metal catalysis.
• Chemical Biology Probes: Utilized to develop molecular probes for studying biological pathways and target engagement.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects in CDMO (Contract Development and Manufacturing Organization) settings.

Basic Information

Product Name	1-Chloro-6-(trifluoromethoxy)isoquinoline
CAS No.	630423-44-8
Molecular Formula	C₁₁H₅ClF₃NO
Molecular Weight	259.61 g/mol
Synonyms	1-Chloro-6-(trifluoromethoxy)isoquinoline; 6-(Trifluoromethoxy)-1-chloroisoquinoline; 1-Chloro-6-trifluoromethoxyisoquinoline; Isoquinoline, 1-chloro-6-(trifluoromethoxy)-; 630423-44-8; 1-Chloro-6-(trifluoromethoxy)isoquinoline CAS 630423-44-8
EINECS	Contact for details

Quality Control

Our 1-Chloro-6-(trifluoromethoxy)isoquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.