Description

5-(Trifluoromethyl)-1(2H)-Isoquinolinone is a specialized heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in the unique combination of the isoquinolinone scaffold and the electron-withdrawing trifluoromethyl group, which is critical for modulating the physicochemical properties of target molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients, where it serves as a key intermediate in medicinal chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the development of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science: Serves as a precursor for creating specialty polymers and organic electronic materials with tailored properties.
• Chemical Synthesis: Acts as a versatile reagent for introducing the trifluoromethyl-substituted isoquinoline moiety into more complex molecular architectures.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies and the exploration of new chemical reactions.

Basic Information

Product Name	5-(Trifluoromethyl)-1(2H)-Isoquinolinone
CAS No.	630423-22-2
Molecular Formula	C10H6F3NO
Molecular Weight	213.16 g/mol
Synonyms	5-(Trifluoromethyl)isoquinolin-1(2H)-one; 1(2H)-Isoquinolinone, 5-(trifluoromethyl)-; 5-Trifluoromethyl-1,2-dihydroisoquinolin-1-one; 5-Trifluoromethyl-2H-isoquinolin-1-one; 5-(Trifluoromethyl)-1,2-dihydroisoquinolin-1-one; 5-(Trifluoromethyl)-2H-isoquinolin-1-one
EINECS	Contact for details

Quality Control

Our 5-(Trifluoromethyl)-1(2H)-Isoquinolinone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.