Description

1-Chloro-7-Fluoro-6-Methoxyisoquinoline is a high-purity, multi-functional heterocyclic building block of significant importance in advanced organic synthesis. Its unique halogenated and methoxylated structure makes it a critical intermediate for constructing complex molecules with tailored biological and material properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and anticancer research.
• Agrochemical Development: Used to create advanced active ingredients for crop protection products, leveraging its halogenated isoquinoline core.
• Organic Light-Emitting Diodes (OLEDs): Serves as a building block for electron-transport or host materials in electronic displays and lighting.
• Material Science Research: Employed in the development of novel organic semiconductors, ligands for catalysis, and specialty polymers.
• Chemical Biology Probes: Utilized as a scaffold for creating fluorescent tags or molecular probes to study biological processes.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds for client R&D projects.

Basic Information

Product Name	1-Chloro-7-Fluoro-6-Methoxyisoquinoline
CAS No.	630422-99-0
Molecular Formula	C₁₀H₇ClFNO
Molecular Weight	211.62 g/mol
Synonyms	1-Chloro-7-fluoro-6-methoxyisoquinoline; 6-Methoxy-1-chloro-7-fluoroisoquinoline; 630422-99-0; 1-Chloro-7-fluoro-6-methoxy-isoquinoline; Isoquinoline, 1-chloro-7-fluoro-6-methoxy-; 1-Chloro-7-fluoro-6-methoxy isoquinoline
EINECS	Contact for details

Quality Control

Our 1-Chloro-7-Fluoro-6-Methoxyisoquinoline is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support development and commercial projects with material meeting stringent in-house specifications, and can provide material tailored to specific customer requirements, including research and GMP grades.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.