Description

5-(6-Chloropyrimidin-4-Yloxy)-1H-Indole is a high-purity, advanced pharmaceutical intermediate characterized by its unique heterocyclic structure. This compound is of significant commercial importance for its role as a key building block in the synthesis of novel, biologically active molecules. It is primarily required by research institutions and pharmaceutical companies engaged in the development of small-molecule therapeutics, particularly within oncology and antiviral drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of targeted kinase inhibitors and other receptor antagonists.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Biochemical Tool Compound: Used in vitro to study specific biological pathways and protein interactions.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of active pharmaceutical ingredients (APIs).
• Academic Research: Utilized in university and institutional labs for fundamental research in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	5-(6-Chloropyrimidin-4-Yloxy)-1H-Indole
CAS No.	630126-16-8
Molecular Formula	C12H8ClN3O
Molecular Weight	245.66 g/mol
Synonyms	5-[(6-Chloro-4-pyrimidinyl)oxy]-1H-indole; 1H-Indole, 5-[(6-chloro-4-pyrimidinyl)oxy]-; 5-(6-Chloro-pyrimidin-4-yloxy)-1H-indole; 5-(6-Chloro-4-pyrimidinyloxy)indole; 630126-16-8; 5-(6-Chloropyrimidin-4-yloxy)indole
EINECS	Contact for details

Quality Control

Our 5-(6-Chloropyrimidin-4-Yloxy)-1H-Indole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.