Description

1H-Indole-1-Carboxylic Acid, 3-(1-Cyano-1-Methylethyl)-6-(Phenylmethoxy)-, 1,1-Dimethylethyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its complex indole-based molecular structure. This compound is critical for enabling sophisticated synthetic pathways in modern drug discovery and development. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the synthesis of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of complex drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Organic Synthesis Research: Used in academic and industrial R&D laboratories for developing new synthetic methodologies and exploring structure-activity relationships (SAR).
• Agrochemical Development: Serves as a precursor in the research and synthesis of novel crop protection agents and pesticides.
• Material Science: Investigated for the creation of specialty polymers and advanced organic materials with specific electronic or photonic properties.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.

Basic Information

Product Name	1H-Indole-1-Carboxylic Acid, 3-(1-Cyano-1-Methylethyl)-6-(Phenylmethoxy)-, 1,1-Dimethylethyl Ester
CAS No.	629662-38-0
Molecular Formula	C24H26N2O3
Molecular Weight	390.48 g/mol
Synonyms	tert-Butyl 3-(1-cyano-1-methylethyl)-6-(benzyloxy)-1H-indole-1-carboxylate; 6-Benzyloxy-3-(1-cyano-1-methylethyl)-1H-indole-1-carboxylic acid tert-butyl ester; 3-(2-Cyano-2-propyl)-6-(phenylmethoxy)-1H-indole-1-carboxylic acid 1,1-dimethylethyl ester; 629662-38-0; BOC-protected indole derivative; Indole-1-carboxylate intermediate
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to stringent quality protocols to ensure batch-to-batch consistency and traceability. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We implement in-process controls and final release testing, including HPLC for assay and related substances, to meet the exacting standards required for pharmaceutical R&D and cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Single Maximum Impurity	≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.