Description

2H-Inden-2-One,1-Ethylidene-1,4,5,6,7,7A-Hexahydro-4-Methoxy-,(1E,4R,7As)-Rel-(9Ci) is a high-purity, stereochemically defined synthetic intermediate of significant interest in advanced organic synthesis. This compound matters for its role as a versatile chiral building block, enabling the construction of complex molecular architectures with precise stereochemical control. It is primarily needed by research institutions and pharmaceutical development teams working on novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of novel therapeutic agents, particularly for complex small-molecule drugs.
• Agrochemical Synthesis: Used in the development of advanced, stereoselective pesticides and herbicides where specific spatial orientation is critical for bioactivity.
• Academic & Industrial Research: A valuable tool for methodological studies in asymmetric synthesis, catalysis, and total synthesis of natural products.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring high enantiomeric purity.
• Material Science Precursor: Potential use as a monomer or precursor for synthesizing novel polymers with specific optical or electronic properties.

Basic Information

Item	Details
Product Name	2H-Inden-2-One,1-Ethylidene-1,4,5,6,7,7A-Hexahydro-4-Methoxy-,(1E,4R,7As)-Rel-(9Ci)
CAS No.	628317-41-9
Molecular Formula	C12H16O2
Molecular Weight	192.26 g/mol
Synonyms	(1E,4R,7aS)-1-Ethylidene-4-methoxy-1,4,5,6,7,7a-hexahydro-2H-inden-2-one; rel-(1E,4R,7aS)-1-Ethylidene-4-methoxy-1,4,5,6,7,7a-hexahydro-2H-inden-2-one; 1-Ethylidene-4-methoxy-1,4,5,6,7,7a-hexahydro-2H-inden-2-one (rel-(1E,4R,7aS)-); 4-Methoxy-1-ethylidene-1,4,5,6,7,7a-hexahydro-2H-inden-2-one; Chiral Hexahydroindenone Derivative; Methoxy-substituted Indanone Intermediate
EINECS	Contact for details

Quality Control

Our 2H-Inden-2-One,1-Ethylidene-1,4,5,6,7,7A-Hexahydro-4-Methoxy-,(1E,4R,7As)-Rel-(9Ci) is produced under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and stereochemical integrity. Certificates of Analysis (COA) detailing specifications such as assay (HPLC), enantiomeric excess, and impurity profiles are provided and available upon request. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storage under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% e.e.
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.