Description

2-Methyl-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenol is a high-purity boronic ester derivative, a crucial building block in modern synthetic organic chemistry. Its primary value lies in its role as a protected phenolic boronic acid, offering enhanced stability and solubility for cross-coupling reactions compared to its free acid form. This compound is essential for researchers and manufacturers in the pharmaceutical and advanced materials sectors who require reliable, high-quality intermediates for constructing complex molecular architectures, such as active pharmaceutical ingredients (APIs) and organic electronic materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for the synthesis of biaryl structures found in various drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides that require specific phenolic-biaryl scaffolds.
• Material Science & OLED Development: Serves as a building block for creating organic light-emitting diode (OLED) materials, liquid crystals, and other advanced functional polymers.
• Ligand & Catalyst Preparation: Employed in the synthesis of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Research & Development: A versatile reagent for academic and industrial R&D labs exploring new synthetic pathways and novel organic compounds.
• Fine Chemical Production: Integral to the multi-step synthesis of complex fine chemicals and specialty performance materials.

Basic Information

Product Name	2-Methyl-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenol
CAS No.	627906-52-9
Molecular Formula	C₁₃H₁₉BO₃
Molecular Weight	234.10 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-methylphenol; 2-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol; 2-Methyl-4-(tetramethyl-1,3,2-dioxaborolan-2-yl)phenol; Phenol, 2-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 4-Pinacolatoboryl-2-methylphenol; 2-Methyl-4-boronophenol pinacol ester
EINECS	Contact for details

Quality Control

Our 2-Methyl-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition. Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Melting Point	Contact for details
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.