Description

1-(3-Bromo-5-Fluorophenyl)Ethanol is a high-purity fluorinated and brominated aromatic alcohol building block. This compound is critical for the synthesis of complex molecules where its halogenated phenyl ring and chiral alcohol functionality enable precise structural modifications. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries. Its unique structure makes it a valuable intermediate for creating active pharmaceutical ingredients (APIs) and advanced material precursors.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, leveraging the halogenated aromatic system for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of specialty monomers for advanced polymers and liquid crystals.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development and quality control in regulated industries.
• Custom Synthesis Building Block: Provides a versatile starting point for contract research organizations (CROs) and fine chemical manufacturers.

Basic Information

Product Name	1-(3-Bromo-5-Fluorophenyl)Ethanol
CAS No.	627527-04-2
Molecular Formula	C8H8BrFO
Molecular Weight	219.05 g/mol
Synonyms	1-(3-Bromo-5-fluorophenyl)ethan-1-ol; (3-Bromo-5-fluorophenyl)methylcarbinol; α-Methyl-3-bromo-5-fluorobenzyl alcohol; 3-Bromo-5-fluoro-α-methylbenzenemethanol; 3'-Bromo-5'-fluoroacetophenone (reduction product); 1-(3-Bromo-5-fluorophenyl)ethyl alcohol
EINECS	Contact for details

Quality Control

Our 1-(3-Bromo-5-Fluorophenyl)Ethanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via NMR and IR spectroscopy, to ensure it meets the exacting standards required for research and commercial synthesis. Certificates of Analysis (COA) with full traceability are provided for every shipment, and we support compliance with cGMP, REACH, and other global regulatory frameworks as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is sensitive to strong alkalis and fluorides; keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0% (Area %)
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (Typical for specific enantiomer)
Water Content (KF)	≤ 0.5% w/w
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.