Description

Ethyl 4-(3-Chloro-6-Fluorobenzo[B]Thiophene-2-Carbonyl)Piperazine-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate of significant importance in modern drug discovery and development. This compound serves as a critical building block for synthesizing novel therapeutic agents, particularly those targeting complex disease pathways. It is primarily required by research institutions and pharmaceutical companies engaged in the development of new chemical entities, especially within oncology and central nervous system (CNS) research.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel small-molecule drug candidates, particularly for targeted therapies.
• Oncology Research: Used in the development of potential kinase inhibitors and other anti-cancer agents due to its benzothiophene and piperazine scaffold.
• CNS Drug Discovery: Serves as a building block for compounds targeting neurological disorders, leveraging its potential for blood-brain barrier penetration.
• Chemical Biology: Employed as a probe or tool compound in biochemical assays to study protein-ligand interactions.
• Process Chemistry & Scale-Up: Used in route scouting and optimization for the commercial-scale production of active pharmaceutical ingredients (APIs).
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting global pharmaceutical R&D pipelines.

Basic Information

Product Name	Ethyl 4-(3-Chloro-6-Fluorobenzo[B]Thiophene-2-Carbonyl)Piperazine-1-Carboxylate
CAS No.	620570-09-4
Molecular Formula	C17H16ClFN2O3S
Molecular Weight	382.84 g/mol
Synonyms	1-(Ethoxycarbonyl)-4-[(3-chloro-6-fluorobenzo[b]thiophen-2-yl)carbonyl]piperazine; Ethyl 1-[(3-chloro-6-fluorobenzo[b]thiophene-2-carbonyl)]piperazine-4-carboxylate; 3-Chloro-6-fluoro-benzo[b]thiophene-2-carboxylic acid (4-ethoxycarbonyl-piperazin-1-yl)-amide; 620570-09-4; UNII-6B9Q8V6A8F; 6B9Q8V6A8F; AKOS040759623; FT-0773297; SCHEMBL23346896.
EINECS	Contact for details

Quality Control

Our Ethyl 4-(3-Chloro-6-Fluorobenzo[B]Thiophene-2-Carbonyl)Piperazine-1-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and compliance with your internal specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.