Description

1-(4-Bromophenyl)-3-(2,4-Dichloro-5-Fluorophenyl)-1H-Pyrazole-4-Carbaldehyde is a high-purity, multi-halogenated pyrazole derivative serving as a critical advanced intermediate for the synthesis of complex active molecules. This compound matters because it provides a versatile halogenated scaffold essential for constructing novel chemical entities with targeted biological or material properties. It is primarily needed by pharmaceutical R&D teams, agrochemical innovators, and specialty chemical manufacturers developing new active ingredients, functional materials, and ligands for catalysis.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and anti-inflammatory research.
• Agrochemical Synthesis: Precursor for developing new-generation herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science Research: Used in the development of organic semiconductors, liquid crystals, and photoactive polymers.
• Chemical Biology: Serves as a probe or linker in the development of biochemical tools and diagnostic agents.
• Catalysis & Ligand Development: The pyrazole core and halogen substituents make it a candidate for designing novel metal-organic frameworks (MOFs) and catalytic ligands.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of client-specific target molecules under cGMP or research-grade conditions.

Basic Information

Product Name	1-(4-Bromophenyl)-3-(2,4-Dichloro-5-Fluorophenyl)-1H-Pyrazole-4-Carbaldehyde
CAS No.	618101-59-0
Molecular Formula	C16H8BrCl2FN2O
Molecular Weight	414.06 g/mol
Synonyms	4-Bromo-2',4'-dichloro-5'-fluorochalcone pyrazole carboxaldehyde; 1-(4-Bromophenyl)-3-(2,4-dichloro-5-fluorophenyl)-1H-pyrazole-4-carboxaldehyde; 4-Formyl-1-(4-bromophenyl)-3-(2,4-dichloro-5-fluorophenyl)pyrazole; Pyrazole-4-carbaldehyde, 1-(4-bromophenyl)-3-(2,4-dichloro-5-fluorophenyl)-; 618101-59-0; SCHEMBL11806227; BRN 12588251
EINECS	Contact for details

Quality Control

Our 1-(4-Bromophenyl)-3-(2,4-Dichloro-5-Fluorophenyl)-1H-Pyrazole-4-Carbaldehyde is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our quality commitment supports applications from research to commercial scale, with the capability to meet specific client protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized; for long-term storage, consider keeping under an inert atmosphere such as nitrogen or argon. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Retention time matches reference standard
Identification (IR)	Spectrum conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.