Description

(5-Amino-1-(4-Chlorophenyl)-1H-Pyrazol-4-Yl)(p-Tolyl)Methanone is a high-purity, functionalized pyrazole derivative of significant interest in advanced organic synthesis. This compound serves as a critical pharmacophore and versatile building block for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily required by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating new molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Research: Used as a core scaffold for developing new-generation herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Chemical Biology Probe: Employed in academic and industrial research to study enzyme inhibition and protein-ligand interactions due to its specific molecular architecture.
• Material Science Precursor: Potential building block for synthesizing organic electronic materials and advanced polymers with specialized properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects requiring this precise chemical entity.

Basic Information

Product Name	(5-Amino-1-(4-Chlorophenyl)-1H-Pyrazol-4-Yl)(p-Tolyl)Methanone
CAS No.	618091-23-9
Molecular Formula	C17H14ClN3O
Molecular Weight	311.77 g/mol
Synonyms	5-Amino-1-(4-chlorophenyl)-1H-pyrazole-4-carboxylic acid p-tolyl ketone; 4-Methylbenzoyl(5-amino-1-(4-chlorophenyl)-1H-pyrazol-4-yl)methanone; 1-(4-Chlorophenyl)-5-amino-1H-pyrazol-4-yl 4-methylphenyl ketone; (5-Amino-1-(4-chlorophenyl)-1H-pyrazol-4-yl)(4-methylphenyl)methanone; p-Tolyl[5-amino-1-(p-chlorophenyl)-1H-pyrazol-4-yl]methanone
EINECS	Contact for details

Quality Control

Our (5-Amino-1-(4-Chlorophenyl)-1H-Pyrazol-4-Yl)(p-Tolyl)Methanone is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request, supporting compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be light-sensitive and hygroscopic; therefore, handling under an inert atmosphere is recommended for long-term storage or when working with large quantities.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.