Description

1-(4-Fluoro-Phenyl)-5-Trifluoromethyl-Pyrazole-4-Carboxylicacidhydrazide is a high-purity, multi-functional pyrazole derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both fluorine and trifluoromethyl groups, is engineered to impart desirable properties such as metabolic stability and enhanced lipophilicity to target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is utilized to create novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in therapeutic areas requiring fluorinated heterocycles.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging the bioactivity-enhancing properties of the fluorine substituents.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Material Science Precursor: Potential use in the synthesis of specialty polymers and advanced materials with specific electronic or surface properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and client-specific projects.

Basic Information

Product Name	1-(4-Fluoro-Phenyl)-5-Trifluoromethyl-Pyrazole-4-Carboxylicacidhydrazide
CAS No.	618090-96-3
Molecular Formula	C11H8F4N4O
Molecular Weight	288.20 g/mol
Synonyms	1-(4-Fluorophenyl)-5-(trifluoromethyl)-1H-pyrazole-4-carbohydrazide; 4-Fluoro-α,α,α-trifluoro-1H-pyrazole-1-acetohydrazide, 5-phenyl-; 5-(Trifluoromethyl)-1-(4-fluorophenyl)-1H-pyrazole-4-carboxylic acid hydrazide; 1H-Pyrazole-4-carboxylic acid, 1-(4-fluorophenyl)-5-(trifluoromethyl)-, hydrazide; 618090-96-3; 1-(4-Fluorophenyl)-5-(trifluoromethyl)pyrazole-4-carbohydrazide
EINECS	Contact for details

Quality Control

Our production of 1-(4-Fluoro-Phenyl)-5-Trifluoromethyl-Pyrazole-4-Carboxylicacidhydrazide adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. All material is subjected to comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and quantify impurities. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting the specific results against agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.