Description

4-Bromo-1-(Toluene-4-Sulfonyl)-1H-Imidazole is a high-purity, advanced pharmaceutical intermediate and versatile building block in organic synthesis. This compound is valued for its role as a key precursor in the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry for creating novel heterocyclic compounds. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new therapeutic agents and functional materials.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel imidazole-based drug candidates, including kinase inhibitors and antiviral agents.
• Agrochemical Research: Used in the development of new fungicides and herbicides that leverage the imidazole sulfonamide scaffold for enhanced bioactivity.
• Organic Synthesis Reagent: Serves as a versatile electrophile or protecting group precursor in complex multi-step synthetic routes, including cross-coupling reactions.
• Material Science: Potential monomer or functional additive in the research of specialty polymers and advanced organic materials.
• Chemical Biology: Employed as a probe or linker in bioconjugation chemistry and the development of biochemical tools.

Basic Information

Item	Details
Product Name	4-Bromo-1-(Toluene-4-Sulfonyl)-1H-Imidazole
CAS No.	615534-48-0
Molecular Formula	C10H9BrN2O2S
Molecular Weight	301.16 g/mol
Synonyms	4-Bromo-1-(p-tolylsulfonyl)-1H-imidazole; 4-Bromo-1-tosyl-1H-imidazole; 1H-Imidazole, 4-bromo-1-[(4-methylphenyl)sulfonyl]-; 4-Bromo-1-(4-methylbenzenesulfonyl)-1H-imidazole; 4-Bromo-1-tosylimidazole; p-Toluenesulfonyl-4-bromoimidazole; Tosyl-4-bromoimidazole; 4-Bromo-1-(p-toluenesulfonyl)imidazole
EINECS	Contact for details

Quality Control

Our 4-Bromo-1-(Toluene-4-Sulfonyl)-1H-Imidazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with cGMP and ISO standards for pharmaceutical intermediate production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.