Description

Phenyl 4,6-o-Benzylidene-2-Deoxy-1-Thio-2-(2,2,2-Trichloroethoxycarbonylamino)-β-D-Glucopyranoside is a sophisticated, high-purity carbohydrate derivative and a key protected thioglycoside intermediate. This compound is critical for synthetic chemists requiring precise stereochemical control and selective deprotection strategies in complex molecule assembly. It is primarily utilized in advanced pharmaceutical research and development, particularly in the synthesis of novel glycoconjugates, glycomimetics, and complex oligosaccharides for therapeutic applications.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of complex carbohydrate-based active pharmaceutical ingredients (APIs) and glycodrugs.
• Glycoconjugate Synthesis: Used in the preparation of glycoproteins, glycolipids, and other biologically relevant glycoconjugates for immunological and drug discovery research.
• Oligosaccharide Assembly: Serves as a key donor molecule in automated and solution-phase oligosaccharide synthesis, leveraging its thioglycoside and orthogonal protecting groups.
• Glycomimetic Development: Enables the creation of stable glycomimetics for studying carbohydrate-protein interactions and developing enzyme inhibitors.
• Chemical Biology Probes: Acts as a precursor for labeled carbohydrate probes used in metabolic labeling and imaging studies within cells.
• Academic & Industrial R&D: Essential for research laboratories in universities, government institutes, and biotech companies focused on glycoscience and medicinal chemistry.

Basic Information

Product Name	Phenyl 4,6-o-Benzylidene-2-Deoxy-1-Thio-2-(2,2,2-Trichloroethoxycarbonylamino)-β-D-Glucopyranoside
CAS No.	613244-81-8
Molecular Formula	C22H22Cl3NO6S
Molecular Weight	534.84 g/mol
Synonyms	Phenyl 4,6-O-Benzylidene-2-deoxy-1-thio-2-[(2,2,2-trichloroethoxy)carbonylamino]-β-D-glucopyranoside; Phenyl 2-Deoxy-2-[(2,2,2-trichloroethoxycarbonyl)amino]-4,6-O-benzylidene-1-thio-β-D-glucopyranoside; 1-Thio-β-D-glucopyranoside, phenyl 4,6-O-benzylidene-2-deoxy-2-[[(2,2,2-trichloroethoxy)carbonyl]amino]-; Troc-protected thioglucoside; Benzylidene-protected Troc-glucosamine thioglycoside; Glycosyl donor with Troc and benzylidene protection; 2-Amino-2-deoxy-β-D-glucopyranoside derivative.
EINECS	Contact for details

Quality Control

Our Phenyl 4,6-o-Benzylidene-2-Deoxy-1-Thio-2-(2,2,2-Trichloroethoxycarbonylamino)-β-D-Glucopyranoside is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical characterization, including HPLC for purity, NMR for structural confirmation, and mass spectrometry for identity verification. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with research-grade specifications. Custom purity grades and analytical packages are available to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions when possible. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen in a desiccator.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.