Description

(4-Iodo-3-Nitro-Phenyl)-Methanol is a specialized aromatic building block featuring both nitro and iodo functional groups on a benzyl alcohol core. This compound matters for its versatility as a key intermediate in the synthesis of complex molecules, particularly in pharmaceutical and advanced material research. It is needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, especially those targeting specific receptors or requiring halogenated aromatic systems.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides where the nitro and iodo substituents contribute to biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and organic synthesis.
• Material Science Research: Employed in the development of organic electronic materials, liquid crystals, and photoactive compounds.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to form biaryl structures.
• Chemical Derivatization: The benzyl alcohol group allows for further functionalization through esterification, etherification, or oxidation to the corresponding aldehyde.

Basic Information

Item	Detail
Product Name	(4-Iodo-3-Nitro-Phenyl)-Methanol
CAS No.	612825-76-0
Molecular Formula	C7H6INO3
Molecular Weight	279.03 g/mol
Synonyms	4-Iodo-3-nitrobenzyl alcohol; (4-Iodo-3-nitrophenyl)methanol; 3-Nitro-4-iodobenzyl alcohol; α-Hydroxymethyl-4-iodo-3-nitrobenzene; 1-(Hydroxymethyl)-4-iodo-3-nitrobenzene; 4-Iodo-3-nitro-benzenemethanol; 4-Iodo-3-nitrobenzylalcohol; 4-Iodo-3-nitro-phenylmethanol
EINECS	Contact for details

Quality Control

Our (4-Iodo-3-Nitro-Phenyl)-Methanol is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. We provide comprehensive Certificates of Analysis (COA) with each shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using a desiccant.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.