Description

3-Thiophenecarbonitrile,2-Amino-5-Cyclopentyl-(9Ci) is a specialized heterocyclic building block featuring a functionalized thiophene core with amino and nitrile substituents. This compound matters as a high-value intermediate for the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to incorporate unique thiophene-based scaffolds into their target compounds.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially in therapeutic areas targeting the central nervous system or as kinase inhibitors.
• Agrochemical Research: Used in the development of new crop protection agents, such as herbicides and fungicides, leveraging its heterocyclic structure.
• Material Science: Serves as a precursor for functionalized polymers or organic electronic materials due to the electron-rich thiophene unit and reactive nitrile group.
• Chemical Synthesis: Employed in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis to explore new chemical spaces.
• Ligand and Catalyst Development: The amino and nitrile functional groups make it a candidate for creating novel ligands in coordination chemistry and catalysis.

Basic Information

Product Name	3-Thiophenecarbonitrile,2-Amino-5-Cyclopentyl-(9Ci)
CAS No.	612504-42-4
Molecular Formula	C10H12N2S
Molecular Weight	192.28 g/mol
Synonyms	2-Amino-5-cyclopentylthiophene-3-carbonitrile; 5-Cyclopentyl-2-aminothiophene-3-carbonitrile; 2-Amino-5-cyclopentyl-3-thiophenecarbonitrile; 2-Amino-5-cyclopentyl-3-cyanothiophene; 3-Cyano-5-cyclopentyl-2-aminothiophene; (9CI) 3-Thiophenecarbonitrile, 2-amino-5-cyclopentyl-; 612504-42-4
EINECS	Contact for details

Quality Control

Our 3-Thiophenecarbonitrile,2-Amino-5-Cyclopentyl-(9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to cGMP principles and adherence to ISO quality standards ensure reliable supply for critical R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.